The growth of new axonal sprouts was studied from transected, ascending noradrenergic axons into transplants of iris tissue in the caudal hypothalamus of the rat. A single intraventricular injection of nerve growth factor, given at the time of axonal damage, resulted in an increased formation and growth of new noradrenaline sprouts 7 days later. The effect seemed to be proportional to the administered dose of nerve growth factor.
No takes yet. Share an insight, caveat, or question.
Björklund et al. (1972) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: