Copper(i) iodide–DMAP catalyzed homo- and heterocoupling of terminal alkynes

A practical and efficient catalytic system comprising CuI and DMAP has been developed for the oxidative homo- and heterocoupling of terminal alkynes under aerobic conditions at room temperature. The catalytic utility of DMAP for efficient oxidative coupling of terminal alkynes has been explored. The CuI–DMAP catalytic system avoids the need for excess base and specialized ligands in oxidative coupling. Short reaction times make this approach economical and environmentally friendly.