What question did this study set out to answer?

To describe clinical characteristics and antiviral therapeutic outcomes in immunocompromised individuals presenting with necrotizing retinitis linked to varicella zoster virus.

January 1, 1987Retina

Presumed Varicella Zoster Retinitis in Immunocompromised Patients

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Authors

DJDouglas A. JabsJohns Hopkins University ASAndrew SchachatCleveland Clinic RLRobert A. LissJohns Hopkins University

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Implication

Case series reports prompt recovery following acyclovir therapy in immunocompromised individuals with necrotizing retinitis, highlighting varicella zoster virus as an underrecognized cause.

Key Points

To describe clinical characteristics and antiviral therapeutic outcomes in immunocompromised individuals presenting with necrotizing retinitis linked to varicella zoster virus.
Evaluated three immunocompromised patients (N=3) presenting with cutaneous herpes zoster and an acute retinal necrosis-like necrotizing retinitis.
Treated all patients with acyclovir targeting presumed varicella zoster virus infection.
All three immunocompromised patients demonstrated prompt clinical improvement of necrotizing retinitis following acyclovir administration.
The clinical presentation mimicked acute retinal necrosis, identifying varicella zoster virus as an important cause of retinitis in immunocompromised hosts alongside cytomegalovirus.

Cite This Study

Jabs et al. (1987) studied this question.

synapsesocial.com/papers/6a85cd79f9a228174586cc16 https://doi.org/10.1097/00006982-198700710-00002

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Implication

Case series reports prompt recovery following acyclovir therapy in immunocompromised individuals with necrotizing retinitis, highlighting varicella zoster virus as an underrecognized cause.

Presumed Varicella Zoster Retinitis in Immunocompromised Patients

Discussion

Member takes

Implication

Key Points

Cite This Study

Presumed Varicella Zoster Retinitis in Immunocompromised Patients

Discussion

Member takes

Implication

Key Points

Cite This Study

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