A novel homomorphic signal processing method enables accurate ultrasonic measurement of thin layers down to 50 µm, showing potential for in vivo arterial wall thickness estimation.
Hypothesis-generating for in vivo arterial wall measurement; requires prospective validation before clinical translation.
A homomorphic signal processing method for accurate thickness measurement of thin layers is presented. The method consists in taking the envelope of the inverse Fourier transform of a corrected logarithmic derivative of the energy spectrum (ES) of the measured signal. Simulations show excellent agreement between estimated and actual values. The method is validated by in vitro experiments at 10 MHz on Teflon films, where thicknesses down to 50 mu m are recovered, and preliminary in vivo results on arterial wall thickness estimates are presented.>
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Meister et al. (1992) studied this question.
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