Oral salt supplementation is an effective treatment for infants with pseudohypoaldosteronism.
May support salt supplementation in pseudohypoaldosteronism; leaves open confirmation in prospective trials.
Two unrelated male infants with pseudohypoaldosteronism are reported. Their main clinical symptom was failure to thrive. Renal and adrenal function were normal. Sodium balance studies showed an abnormal urinary salt loss in the presence of very high aldosterone secretion rates. A daily oral administration of salt supplement resulted in a complete therapeutic success. A brief review of the literature on this rare condition is given and the pathophysiology is discussed.
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Willem Proesmans (1973) studied this question.
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