Why the study?
Is mean platelet volume significantly increased in patients with acute coronary syndrome compared to healthy controls?
Is mean platelet volume significantly increased in patients with acute coronary syndrome compared to healthy controls?
Mean platelet volume is significantly elevated in patients with acute coronary syndrome compared to healthy controls, suggesting its potential utility as a simple, accessible biomarker for cardiovascular risk stratification.
AIM: To study the mean platelet volume in acute coronary syndrome patients and compare it with non acute coronary syndrome patients. MATERIALS AND METHODS: This is a casecontrol study carried out between November 2012 to October 2013 at the Department of Internal Medicine and the Department of Cardiology, Government Medical College, Jammu. A total of 200 subjects were evaluated after applying proper inclusion and exclusion criterias. These included 100 cases with acute coronary syndromes and 100 age and sex matched controls. Measurement of mean platelet volume was done in both and and analysis of other variables like hypertension, diabetes, body mass index, smoking, alcohol, family history, etc was done with respect to mean platelet volume. The results were compiled statistically using student t -test and ANOVA. RESULTS: The mean age of cases was 47.607.12 years, while the mean age of controls was 44.34 7.44 years. The mean platelet volume in cases was 9.33 1.03 fL, while in controls it was 7.05 0.32 fL. When this was statistically compared a highly significant (p=.000) relationship between them was found.
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Abrol et al. (2015) studied this question.
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