What question did this study set out to answer?

To evaluate adherence to clinical guidelines for baseline assessment and ongoing surveillance of adverse reactions in patients receiving chronic amiodarone therapy.

January 1, 2019Health Services Research and Managerial EpidemiologyOpen Access

Adherence to Monitoring Guidelines of Amiodarone Adverse Reactions

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Why the study?

Amiodarone frequently causes adverse reactions and clinical guidelines warrant pre-treatment assessment and repeated monitoring, but adherence to these guidelines needed evaluation.

What is the rate of adherence to clinical guidelines for monitoring amiodarone adverse reactions in adult patients on chronic therapy?

Design

Retrospective chart review

Authors

OLOphir LavonTechnion – Israel Institute of Technology RGRon GoldmanIsrael Oceanographic and Limnological Research

Discussion

Member takes

Implication

Suboptimal amiodarone monitoring adherence persists; leaves open whether targeted interventions can improve thyroid and pulmonary surveillance rates.

Key Points

To evaluate adherence to clinical guidelines for baseline assessment and ongoing surveillance of adverse reactions in patients receiving chronic amiodarone therapy.
Retrospective chart review of electronic medical records.
Included adult patients receiving oral amiodarone therapy for at least 12 months (N=100).
Baseline evaluations were completed for thyroid and liver function in 97% of patients, chest X-ray in 84%, ophthalmology in 64%, and respiratory function tests in 2%.
During maintenance therapy, 6-month monitoring was completed for liver function in 96% and thyroid function in 59%, annual cardiac reassessment occurred in 50%, annual chest X-rays occurred in 0%, and routine neurological or dermatological exams were absent.

Structured PICO

What is the rate of adherence to clinical guidelines for monitoring amiodarone adverse reactions in adult patients on chronic therapy?

Population

100 adult patients treated with oral amiodarone for at least 12 months

Intervention

Monitoring for amiodarone adverse reactions according to clinical guidelines

Outcome

Adherence to clinical guidelines for monitoring amiodarone adverse reactionssafety

Adherence to recommended clinical guidelines for monitoring amiodarone adverse reactions is poor, particularly for long-term thyroid, pulmonary, and cardiac surveillance.

Cite This Study

Lavon et al. (2019) studied this question.

synapsesocial.com/papers/6a864734894d3eb3a35aeade https://doi.org/10.1177/2333392819844635

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Implication

Suboptimal amiodarone monitoring adherence persists; leaves open whether targeted interventions can improve thyroid and pulmonary surveillance rates.

Adherence to Monitoring Guidelines of Amiodarone Adverse Reactions

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Adherence to Monitoring Guidelines of Amiodarone Adverse Reactions

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider