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June 1, 1990The LancetOpen Access

HTLV-I/II seropositivity and death from AIDS among HIV-1 seropositive intravenous drug users

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Why the study?

Does HTLV-I/II co-infection increase the risk of death from AIDS in HIV-1 seropositive intravenous drug users?

Population

107 HIV-1 seropositive intravenous drug users from a cohort of 230 street-recruited IVDUs in Miami, Florida…

Comparison

Co-infection with human T-lymphotropic virus… vs HIV-1 seropositive only (HTLV-I/II negative)

Design

Cohort

Authors

JPJ. Bryan PageUniversity of California, RiversideSLShenghan LaiPreventive CardiologyDCDale D. ChitwoodUniversity of Miami

Discussion

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Implication

Co-infection associated with higher AIDS mortality in HIV+ IVDUs; hypothesis-generating, should not yet change practice.

Structured PICO

Does HTLV-I/II co-infection increase the risk of death from AIDS in HIV-1 seropositive intravenous drug users?

P
Population
107 HIV-1 seropositive intravenous drug users (IVDUs) from a cohort of 230 street-recruited IVDUs in Miami, Florida, USA
I
Intervention
Co-infection with human T-lymphotropic virus type I or II (HTLV-I/II) (n=23)
C
Comparator
HIV-1 seropositive only (HTLV-I/II negative)
O
Outcome
Death from AIDShard clinical

HTLV-I/II co-infection in HIV-1 seropositive intravenous drug users is associated with a threefold increased risk of death from AIDS.

Cite This Study

Page et al. (1990) studied this question.

synapsesocial.com/papers/6a8648e2fb63d0a2a03a666ahttps://doi.org/10.1016/0140-6736(90)91456-k
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