Are Insulin Resistance Index, IGF-1 and Metabolic Syndrome Components Correlates with Severe Preeclampsia?

OBJECTIVE: Analyse the relation between insulin resistance and severe preeclampsia (SPE). METHODS: Case control study paired by body mass index and gestational age; including 16 patients with severe SPE and 16 normotensive controls. Insulin resistance was assessed through the HOMA-IR and QUICKI-IS indexes. RESULTS: There was no significant difference between the groups regarding the HOMA-IR and QUICKI-IS indexes and HDL cholesterol. Triglyceride levels were higher and the IGF-1 was lower in the SPE group than in the control group. CONCLUSIONS: There were no differences in the insulin resitance indexes between the group with SPE and normal controls.