Population
Foot-and-mouth disease virus (FMDV) RNA and replicative forms isolated from infected cells
Design
Preclinical
Authors
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Does not inform FMDV control strategies; leaves open whether poly(G)-mediated replication applies beyond this animal model.
The study provides unequivocal evidence that the poly(C) tract in FMDV RNA is replicated via a poly(G) tract in the negative strand.
Mellor et al. (1985) studied this question.
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