Highlights the role of autonomic nervous system dysregulation in the development of cardiovascular diseases, metabolic syndrome, and syncopal conditions in children.
Does not support practice changes in children; leaves open whether autonomic-targeted interventions improve cardiovascular or metabolic outcomes.
Most cardiac diseases, which are the leading cause of death and disability worldwide, come from the dysfunction of the autonomic nervous system. Autonomic dysregulation is the main pathogenic cause of the orthostatic dysregulation syndromes and neurotransmitter syncopal conditions. Overactivity of the sympathoadrenal department of the autonomic nervous system contributes to the development of type 2 diabetes mellitus, metabolic syndrome and obstructive breathing disorders during sleep, which are closely associated with the development of cardiovascular diseases.
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Творогова et al. (2017) studied this question.
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