Why the study?
Does chronic exposure to dialysis fluid reduce peritoneal ultrafiltration capacity in rats?
Population
21 rats (11 experimental, 10 control)
Comparison
Twice-daily intraperitoneal injections of 20 mL… vs No injections
Design
Preclinical
Follow-up
6 weeks
Authors
Loading...
Suggests ultrafiltration impairment risk from chronic dialysis fluid in rats; leaves open translation to human PD patients.
Does chronic exposure to dialysis fluid reduce peritoneal ultrafiltration capacity in rats?
Chronic exposure to hypertonic dialysis fluid in rats leads to a significant loss of peritoneal ultrafiltration capacity and increased glucose absorption.
Slater et al. (1992) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: