Answers are grounded in this paper and cite their sources.
In Brief A 65-year-old woman received injections of Restylane, cross-linked hyaluronic acid, for the intended cosmetic filling of periorbital rhytids. The achieved result was undesirable, and the filler lasted more than 5 years. Hyaluronidase administered directly beneath the treated areas resulted in rapid resolution of the Restylane effect. Hyaluronidase reversed a long-standing, undesirable effect of Restylane injections.
No takes yet. Share an insight, caveat, or question.
Soparkar et al. (2004) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: