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In this issue of Blood, Pleyer and colleagues report results from 2 studies assessing differences in the humoral response to 2 different vaccines in patients with chronic lymphocytic leukemia (CLL) on observation or receiving a Bruton tyrosine kinase inhibitor (BTKi).1 Their findings have immediate clinical implications and call for research preparedness as we eagerly anticipate access to vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the near future.
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Shadman et al. (2021) studied this question.
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