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November 11, 2010Journal of VirologyOpen Access

Identification of Amino Acids in the Human Tetherin Transmembrane Domain Responsible for HIV-1 Vpu Interaction and Susceptibility

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Authors

TKTomoko KobayashiTokyo University of AgricultureHOHirotaka OdeNational Hospital OrganizationTYTakeshi YoshidaTokyo Medical and Dental University

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Kobayashi et al. (2010) studied this question.

synapsesocial.com/papers/6a86665b79a480030073ae2ehttps://doi.org/10.1128/jvi.01668-10
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Antiviral Activity of the Interferon-Induced Cellular Protein BST-2/Tetherin2009 · 91 citations
  2. 2HM1.24 Is Internalized from Lipid Rafts by Clathrin-mediated Endocytosis through Interaction with α-Adaptin2009 · 135 citations
  3. 3The Transmembrane Domain of BST-2 Determines Its Sensitivity to Down-Modulation by Human Immunodeficiency Virus Type 1 Vpu2009 · 113 citations
  4. 4HIV-1 Vpu Neutralizes the Antiviral Factor Tetherin/BST-2 by Binding It and Directing Its Beta-TrCP2-Dependent Degradation2009 · 301 citations