Why the study?
Does the Six-Minute Walk Test correlate with established outcome measures and demonstrate fatigue in ambulatory patients with spinal muscular atrophy?
Population
18 ambulatory participants with spinal muscular atrophy (SMA)
Design
Cross-sectional
Authors
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Supports 6MWT evaluation in SMA trials; hypothesis-generating and requires prospective validation before practice change.
Does the Six-Minute Walk Test correlate with established outcome measures and demonstrate fatigue in ambulatory patients with spinal muscular atrophy?
The 6MWT is a safe, objective measure that correlates with established functional scales and is sensitive to motor fatigue in ambulatory patients with SMA, making it a promising outcome measure for clinical trials.
Montes et al. (2010) studied this question.
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