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A retrospective study of tuberous sclerosis in 45 children aged six months to 14 years was done. Positive neuroradiologic findings were present in all, often before the clinical diagnosis was suspected. Pneumoencephalography revealed definite nodules in almost all cases; mild ventricular dilatation was also a common finding. Children are less likely to have intracranial calcification than adults, but the incidence of these calcifications increases with age.
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Fitz et al. (1974) studied this question.
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