DISSEMINATED infections in man due to fungi classified in the family cryptococcaceae are caused usually by Cryptococcus neoformans and by species of candida. The other species included in this family are generally considered to be nonpathogenic and include rhodotorula, a red-colored cryptococcus, species of torulopsis, a small yeast that experimentally bears some similarity to Histoplasma capsulatum in organ distribution and histologic findings,1 and C. neoformans (var. innocuous), which can be separated from the virulent C. neoformans by its failure to multiply significantly at 37°C. and its inability to produce progressive disease in laboratory animals.Severe disease in man due . . .
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Louria et al. (1960) studied this question.
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