Clinical review outlines diagnostic criteria for macrocytosis in clinical populations, highlighting the role of mean corpuscular volume in evaluating megaloblastic anemia.
The term macrocytosis refers to a blood condition in which red blood cells (RBC) are larger than normal. Macrocytosis is reported in terms of mean corpuscular volume (MCV). Normal MCV values range from 80 to 100 femtoliters (fl) and vary by age and reference laboratory. 1 MCV is calculated according to the following formula:
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Aslinia et al. (2006) studied this question.
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