The effect of iron replacement on hba1c in iron deficiency anemia: a before & after study

This is the authors' abstract. We don't add key points for this paper.

Glycated haemoglobin (HbA1c) is used in diagnosis & monitoring of diabetes mellitus & was found to be affected by many factors other than blood glucose; iron deficiency anemia is one of them. In our study 50 patients of iron deficiency anemia were included. All were non-diabetic based on fasting blood sugar (FBS), post prandial blood sugar (PPBS) level & history. HbA1c level, serum ferritin & iron level were calculated before & after 6 months of iron replacement. It was found that after iron therapy HbA1c level was significantly decreased & serum ferritin & serum iron level were significantly increased. Serum ferritin & iron level were negatively correlated to HbA1c before therapy & after that serum iron was positively correlated but serum ferritin remained negatively correlated to HbA1c level. Importantly FBS before & after treatment remained significantly positively correlated as was PPBS. HbA1c level was reduced with iron replacement in iron deficiency anemia independent of blood sugar.