Why the study?
Does preoperative TTE-based graft sizing using leaflet length or area formulas reduce the incidence of residual aortic regurgitation in patients undergoing David reimplantation?
Does preoperative TTE-based graft sizing using leaflet length or area formulas reduce the incidence of residual aortic regurgitation in patients undergoing David reimplantation?
Preoperative TTE-derived formulas based on leaflet length or area may help optimize graft sizing and reduce residual aortic regurgitation in patients undergoing the David reimplantation technique.
TTE-based undersizing may lower mild AR after David reimplantation; hypothesis-generating and should not yet change practice.
OBJECTIVES: Selection of tubular graft size during David reimplantation technique for aortic root dilatation is based on perioperative leaflet height measurements. The present study evaluated whether transthoracic echocardiography (TTE)-based algorithms may help in selecting the graft size preoperatively. METHODS: Thirty patients (52 ± 11 years old, 73% men) who underwent David reimplantation technique were evaluated. The implanted graft size was based on the David's formula. Leaflet height [diameter = 1.1 × ((2 × 2/3 × leaflet height) + 2)), leaflet length (diameter = ((2 × 2/3 × leaflet length) + 2)] and leaflet area [diameter = 0.8 × ((2 × √(total leaflet area/π)) + 2)] TTE-derived formulas were retrospectively developed. The percentage of under- or oversized implanted grafts was calculated and the association between the adequacy of graft sizing using TTE-derived formulas and the incidence of residual aortic regurgitation (AR) was evaluated retrospectively. RESULTS: The incidence of postoperative mild residual AR was 23%. The true diameter of the inplanted graft was oversized based on leaflet height in 15 (50%) patients, based on leaflet length in 13 (43%) patients and based on leaflet area TTE-derived formula in 11 (37%) patients. The incidence of mild AR was significantly lower in undersized grafts compared with oversized grafts based on leaflet length TTE-derived formula (6 vs 46%, P = 0.032) and leaflet area TTE-derived formula (5 vs 55%, P = 0.009). CONCLUSIONS: In patients undergoing David reimplantation technique, grafts considered undersized according to the leaflet length or leaflet area TTE-derived formula were associated with less incidence of residual AR than patients with oversized grafts.
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Regeer et al. (2015) studied this question.
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