What question did this study set out to answer?

To determine whether gastrointestinal dysfunction, marked by an inability to tolerate enteral nutrition, serves as a significant prognostic factor for hospital mortality in critically ill patients.

October 1, 1987Critical Care Medicine

Gastrointestinal dysfunction among intensive care unit patients

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Authors

RCRené ChangSt George's Hospital SJSydney JacobsBeaumont Hospital, Royal Oak BLBerni LeeCoventry University

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Implication

Comparative cohort study demonstrates increased mortality from enteral nutrition intolerance in intensive care patients, indicating gastrointestinal failure marks severe underlying physiologic...

Key Points

To determine whether gastrointestinal dysfunction, marked by an inability to tolerate enteral nutrition, serves as a significant prognostic factor for hospital mortality in critically ill patients.
Evaluated 208 ICU patients without recent bowel surgery, comparing 111 patients who tolerated enteral nutrition (EN) against 97 patients who failed EN and received total parenteral nutrition (TPN).
Selected and matched groups using baseline Acute Physiological and Chronic Health Evaluation (APACHE II) scores (mean 17.7 ± 6.5 in the EN group vs. 17.7 ± 5.1 in the TPN group).
Hospital mortality was significantly higher in patients with GI dysfunction (51%) than in patients with a functioning gut (25%, p < 0.0005).
Patients with GI dysfunction had significantly worse APACHE II physiological subscores for mean blood pressure, oxygenation, and serum creatinine.

Cite This Study

Chang et al. (1987) studied this question.

synapsesocial.com/papers/6a8671404c7902adb32fe28f https://doi.org/10.1097/00003246-198710000-00003

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Implication

Comparative cohort study demonstrates increased mortality from enteral nutrition intolerance in intensive care patients, indicating gastrointestinal failure marks severe underlying physiologic...

Gastrointestinal dysfunction among intensive care unit patients

Discussion

Member takes

Implication

Key Points

Cite This Study

Gastrointestinal dysfunction among intensive care unit patients

Discussion

Member takes

Implication

Key Points

Cite This Study

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