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December 1, 1999Journal of VirologyOpen Access

A Single Nucleotide Change in the 5′ Noncoding Region of Sindbis Virus Confers Neurovirulence in Rats

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Authors

DKDavid KobilerIsrael Institute for Biological Research
Charles M. Rice
Charles M. RiceUniversity of Notre DameCBChaya BrodieBar-Ilan University

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Kobiler et al. (1999) studied this question.

synapsesocial.com/papers/6a867545169aec2a7f0f77aehttps://doi.org/10.1128/jvi.73.12.10440-10446.1999
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Age-Dependent Resistance of Mice to Sindbis Virus Infection: Viral Replication as a Function of Host Age1971 · 56 citations
  2. 2Roles and reactivities of antibodies to alphaviruses1995 · 17 citations
  3. 3Mutations within the 5' nontranslated region of hepatitis A virus RNA which enhance replication in BS-C-1 cells1992 · 73 citations
  4. 4An influenza A virus containing influenza B virus 5' and 3' noncoding regions on the neuraminidase gene is attenuated in mice.1991 · 96 citations
  5. 5Attenuating mutations in glycoproteins E1 and E2 of Sindbis virus produce a highly attenuated strain when combined in vitro1990 · 45 citations