Why the study?
Although HbA1c is considered a prognostic factor in some CAD subgroups, its specific relationship with long-term all-cause death remains controversial.
Does HbA1c level predict long-term all-cause mortality in patients with coronary artery disease?
Population
37,596 CAD patients at Guangdong Provincial People's Hospital
Comparison
Baseline HbA1c quartiles (≤ 5.7%, 5.7% to ≤ 6.1%, 6.1% to ≤ 6.7%, > 6.7%)
Design
Observational cohort study
Follow-up
Median 4 years
Authors
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HbA1c extremes linked to higher CAD mortality; leaves open optimal targets and need for interventional trials.
Does HbA1c level predict long-term all-cause mortality in patients with coronary artery disease?
In patients with coronary artery disease, both low (≤ 5.7%) and high (> 6.7%) HbA1c levels are associated with increased long-term all-cause mortality, forming a U-shaped risk curve.
Liu et al. (2021) studied this question.
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