Diagnostics Using Multiplexed Electrochemical Readout Devices

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Molecular diagnostics of human diseases requires the development of analytical tools with the capacity of simultaneously detecting several biomarkers of interest, mainly proteins and nucleic acids. Until now, most multiplexed analyses have been performed in a microarray format and using optical detection, these showing some limitations in terms of cost, portability and integration into point‐of‐care medical devices. In this context, electrochemical detection can offer an alternative to optical systems due to their high sensitivity, low‐cost, easy miniaturization and integration in compact analytical devices. This article reviews most relevant electroanalytical systems developed so far for multiplexed analysis of DNA and proteins.