Inhibition of the Bursa of Fabricius and the Stilboestrol-Stimulated Oviduct of the Domestic Chick

WITHIN recent years the domestic bird has been used to an increasing extent in physiologic and endocrinologic studies. Some of these investigations have revealed inherent differences between the bird and the mammal (Jailer and Boas, 1950; Zarrow and Baldini, 1952; Morris, 1953; Newcomer, 1959; Nalbandov, 1953). Recently the advent of many new steroids has led to extensive studies on these compounds in the mammal but little work has been done in the bird. The present investigation is concerned with the effect of some of these compounds in the chick and and is designed to determine whether the differences in the action of these compounds in the chick and rat are of a quantitative or qualitative nature and to determine whether some structure-function relationship can be obtained. MATERIAL AND METHODS The chick oviduct test was carried out on 16-day-old chicks of the White Leghorn strain. All birds were injected intramuscularly for …