Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 24, 2012Journal of Veterinary Internal MedicineOpen Access

Cardiac Troponin I in Racing Standardbreds

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does racing increase plasma cTnI concentrations in healthy Standardbred racehorses 1-2 hours post-race?

Population

586 apparently healthy Standardbred racehorses aged 2-14 years

Comparison

Racing (high intensity, short duration exercise) vs Before racing (baseline)

Design

Preclinical

Follow-up

1-2 hours after race

Authors

JSJ. SlackUniversity of PennsylvaniaRBR.C. BostonUniversity of SheffieldLSLori SomaCity Of Hope National Medical Center

Discussion

Loading...

Member takes

Implication

Establishes preliminary cTnI thresholds in healthy racehorses; leaves open validation in broader equine cohorts and clinical disease states.

Structured PICO

Does racing increase plasma cTnI concentrations in healthy Standardbred racehorses 1-2 hours post-race?

P
Population
586 apparently healthy Standardbred racehorses aged 2-14 years
I
Intervention
Racing (high intensity, short duration exercise)
C
Comparator
Before racing (baseline)
O
Outcome
Plasma cardiac troponin I concentrations (95th and 99th percentile upper reference limits) and difference before and after racingsurrogate

In healthy Standardbred racehorses, the 99th percentile upper reference limit for cTnI is 0.06 ng/mL, and concentrations do not significantly increase 1-2 hours after racing.

Limitations

  • Lack of standardization across cTnI assays (limits apply only to the Stratus CS immunoassay)
  • Sampling time of 1-2 hours post-race may be too early to detect increases

Cite This Study

Slack et al. (2012) studied this question.

synapsesocial.com/papers/6a868df7a84787178e75e4dahttps://doi.org/10.1111/j.1939-1676.2012.00969.x
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cardiac Biomarkers and Exercise Duration and Intensity During a Cycle-Touring Event2009 · 45 citations
  2. 2Differential reactivity of cardiac and skeletal muscle from various species in a cardiac troponin I immunoassay1997 · 177 citations
  3. 3Clinical and Analytical Performance of the Liaison Cardiac Troponin I Assay in Unstable Coronary Artery Disease, and the Impact of Age on the Definition of Reference Limits. A FRISC-II Substudy2003 · 55 citations
  4. 4Acute effects of short duration, maximal exercise on cardiac troponin I in healthy horses2006 · 37 citations
  5. 5Cardiac troponin I is a sensitive, specific biomarker of cardiac injury in laboratory animals2006 · 307 citations