What question did this study set out to answer?

To systematically assess the prevalence and distribution of the plasmid-mediated colistin resistance gene mcr-1 in Escherichia coli isolated from German livestock and food chains between 2010 and 2015.

July 25, 2016PLoS ONEOpen Access

Prevalence of mcr-1 in E. coli from Livestock and Food in Germany, 2010–2015

View Full Paper

Ask AI

Bookmark

Authors

AIAlexandra IrrgangFederal Institute for Risk Assessment NRNicole RoschanskiLandesamt für Landwirtschaft, Umwelt und ländliche Räume BTBernd‐Alois TenhagenUniversity of Hohenheim

Discussion

Member takes

Implication

Surveillance study uncovers varying prevalence of the colistin resistance gene mcr-1 across livestock food chains, highlighting poultry as a primary reservoir.

Key Points

To systematically assess the prevalence and distribution of the plasmid-mediated colistin resistance gene mcr-1 in Escherichia coli isolated from German livestock and food chains between 2010 and 2015.
Screened over 10,600 E. coli isolates collected during national zoonotic agent monitoring (2010–2015) in Germany for phenotypic colistin resistance defined by a minimum inhibitory concentration >2 mg/L.
Tested 505 colistin-resistant isolates for the mcr-1 gene using a newly developed TaqMan-based real-time PCR assay.
Detected mcr-1 in 402 isolates, accounting for 79.8% of colistin-resistant isolates and an overall prevalence of 3.8% across all tested E. coli.
Identified the highest mcr-1 prevalence in the turkey food chain (10.7%) and broiler chickens (5.6%), low prevalence in pigs, veal calves, and laying hens, and zero detection in beef cattle, beef, and dairy products.

Cite This Study

Irrgang et al. (2016) studied this question.

synapsesocial.com/papers/6a86936636af4c851489c439 https://doi.org/10.1371/journal.pone.0159863

View Full Paper

Ask AI

Bookmark

Implication

Surveillance study uncovers varying prevalence of the colistin resistance gene mcr-1 across livestock food chains, highlighting poultry as a primary reservoir.

Prevalence of mcr-1 in E. coli from Livestock and Food in Germany, 2010–2015

Discussion

Member takes

Implication

Key Points

Cite This Study

Prevalence of mcr-1 in E. coli from Livestock and Food in Germany, 2010–2015

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider