Why the study?
Does antidepressant treatment reduce major adverse cardiovascular events in patients referred for exercise stress tests?
Does antidepressant treatment reduce major adverse cardiovascular events in patients referred for exercise stress tests?
Antidepressant use is associated with a significantly reduced risk of major adverse cardiovascular events in patients undergoing stress testing, independent of baseline CVD or depression status.
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Antidepressant use may lower MACE risk in stress-tested patients; leaves open causality and requires randomized confirmation before practice change.
Lavoie et al. (2018) studied this question.
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