May 6, 1999New England Journal of Medicine
Acute Necrotizing Pancreatitis
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Discussion
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Implication
Clinical review demonstrates a management paradigm shift toward conservative intensive care in acute necrotizing pancreatitis, indicating the value of delayed or selective intervention.
Key Points
- To review the clinical characteristics of acute necrotizing pancreatitis and outline evolving paradigms in medical and surgical management.
- Synthesis of clinical protocols, imaging criteria, and intervention thresholds for severe acute pancreatitis characterized by glandular necrosis.
- Pancreatic glandular necrosis substantially increases patient morbidity and mortality, with risk escalating significantly in the presence of infection.
- Therapeutic strategies have largely transitioned away from routine early surgical necrosectomy toward aggressive medical stabilization and selective, delayed interventions.
Cite This Study
Baron et al. (1999) studied this question.