Why the study?
Conversion of one-anastomosis gastric bypass to Roux-en-Y gastric bypass is increasing, but its safety and efficacy needed determination.
Does conversion from OAGB to RYGB improve reflux and weight outcomes in patients with severe obesity?
Does conversion from OAGB to RYGB improve reflux and weight outcomes in patients with severe obesity?
Conversion from OAGB to RYGB effectively resolves biliary reflux but is associated with mild medium-term weight regain.
Evidence on OAGB-to-RYGB conversion remains limited; leaves open need for prospective safety data before wider adoption.
One-anastomosis gastric bypass (OAGB) is an effective procedure to treat severe obesity. However, conversion to Roux-en-Y gastric bypass (RYGB) is increasing. We therefore conducted a systematic review to determine the safety and efficacy associated with OAGB-RYGB conversion. A systematic search was conducted by three independent reviewers using Medline, Embase, and the Cochrane library following PRISMA guidelines. Six studies including 134 patients were selected who were undergoing OAGB-RYGB conversion. The most common indications were reflux (47.8%), malnutrition (31.3%), and inadequate weight loss (8.2%). Study outcomes demonstrated 100% resolution of bile reflux. Overall, there was medium-term weight gain of 0.61 BMI. OAGB to RYGB conversion leads to resolution of reflux symptoms. However, it is associated with weight regain, albeit this may be acceptable to patients to treat biliary reflux.
No takes yet. Share an insight, caveat, or question.
Sargsyan et al. (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: