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September 1, 1976Cancer

Methotrexate and citrovorum factor rescue in the management of childhood lymphosarcoma and reticulum cell sarcoma (non-Hodgkin's lymphomas).Prolonged Unmaintained Remissions

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IDIsaac DjerassiMercy Catholic Medical CenterJKJung‐Sun KimInterventional / Structural Cardiology

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Djerassi et al. (1976) studied this question.

synapsesocial.com/papers/6a869cde05076cf37f2d7cc6https://doi.org/10.1002/1097-0142(197609)38:3<1043::aid-cncr2820380302>3.0.co;2-u
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Phase I study of high doses of methotrexate with citrovorum factor in patients with lung cancer1972 · 124 citations
  2. 2Continuous infusion of methotrexate in children with acute leukemia1967 · 89 citations
  3. 3Prevention of Chemotherapeutic Effects of 4-Amino-N10-Methyl-Pteroyl-glutamic Acid on Mouse Leukemia by Citrovorum Factor.1950 · 40 citations
  4. 4Modification of Treatment Schedules in the Management of Advanced Mouse Leukemia with Amethopterin1956 · 122 citations