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Population
Children requiring reduction of upper and lower extremity fractures
Comparison
Low-dose intravenous ketamine bolus vs conventional technique
Design
Randomised controlled clinical trial
Supports ketamine as first-line pediatric ED sedation; reinforces guideline recommendations while extending evidence for procedural use.
Recently, ketamine has been introduced as a common drug given to sedate children for different painful procedures in the emergency department (ED) (6-8). Ketamine is one of the phencyclidine derivatives with quick onset and short duration of action (9), which is cost-effective, easily accessible, stable at room temperature and has safe sedation and analgesia recommended by the World Health Organization, as an essential medication for
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Isfahani et al. (2020) studied this question.
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