Why the study?
Does intravenous piroximone improve left ventricular function and anginal threshold in patients with coronary artery disease?
Population
16 patients with coronary artery disease (CAD)
Comparison
Piroximone 0.75 mg/kg intravenously vs Baseline (before piroximone administration)
Design
Case_series
Authors
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Should not yet change CAD practice; hypothesis-generating for piroximone in LV dysfunction.
Does intravenous piroximone improve left ventricular function and anginal threshold in patients with coronary artery disease?
Intravenous piroximone safely improves left ventricular function through both unloading and positive inotropy in patients with coronary artery disease without inducing angina.
Thormann et al. (2005) studied this question.
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