What question did this study set out to answer?

To evaluate the effect of hydrophilic versus hydrophobic single-piece acrylic intraocular lens materials on the development of posterior capsule opacification at one year post-cataract surgery.

April 1, 2005Journal of Cataract & Refractive Surgery

Comparison of posterior capsule opacification rates between hydrophilic and hydrophobic single-piece acrylic intraocular lenses

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Authors

CHCatherine J. HeatleyCharing Cross Hospital DSDavid J. SpaltonKing's College - North Carolina AKAnupma KumarUnited Lincolnshire Hospitals NHS Trust

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Implication

Randomized trial demonstrates higher posterior capsule opacification with hydrophilic versus hydrophobic acrylic intraocular lenses in cataract patients, highlighting the role of lens material and...

Key Points

To evaluate the effect of hydrophilic versus hydrophobic single-piece acrylic intraocular lens materials on the development of posterior capsule opacification at one year post-cataract surgery.
Prospective randomized trial including 106 eyes of 53 patients with bilateral cataract and no other ocular comorbidity, who were randomized to receive a hydrophobic or hydrophilic single-piece acrylic intraocular lens in the first eye and the alternate lens in the fellow eye 4 to 6 weeks later.
All procedures were performed by a single surgeon, with follow-ups scheduled at 1 day, 1 and 6 months, and 1 year.
Posterior capsule opacification was quantified as percentage area of opacified capsule from high-intensity digital retroillumination photographs by a single operator using dedicated software.
At one year postoperatively, the median percentage area of posterior capsule opacification was 50.3% in the hydrophilic intraocular lens group compared to 4.9% in the hydrophobic intraocular lens group (P < .001).
Lens epithelial cells primarily invaded the posterior capsule at the haptic-optic junction, an effect that was more pronounced in the hydrophilic lens group.

Cite This Study

Heatley et al. (2005) studied this question.

synapsesocial.com/papers/6a86a3f13e22360d2d0cfcbc https://doi.org/10.1016/j.jcrs.2004.08.060

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Implication

Randomized trial demonstrates higher posterior capsule opacification with hydrophilic versus hydrophobic acrylic intraocular lenses in cataract patients, highlighting the role of lens material and...

Comparison of posterior capsule opacification rates between hydrophilic and hydrophobic single-piece acrylic intraocular lenses

Discussion

Member takes

Implication

Key Points

Cite This Study

Comparison of posterior capsule opacification rates between hydrophilic and hydrophobic single-piece acrylic intraocular lenses

Discussion

Member takes

Implication

Key Points

Cite This Study

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