Why the study?
Elevated noise, reduced spatiotemporal resolution, and complex anatomy in ultrasound hinder models from accurately capturing structural relationships and dynamic patterns in echocardiographic segmentation.
The MSV-Mamba deep learning model improves the accuracy of echocardiographic segmentation of the left ventricle compared to existing methods.
Mamba-based echo segmentation may improve analysis amid noise; leaves open prospective clinical validation before workflow adoption.
Echocardiographic image segmentation plays a crucial role in analyzing cardiac function and diagnosing cardiovascular diseases. Ultrasound imaging frequently encounters challenges, such as those related to elevated noise levels, diminished spatiotemporal resolution, and the complexity of anatomical structures. These factors significantly hinder the model’s ability to accurately capture and analyze structural relationships and dynamic patterns across various regions of the heart. Mamba, an emerging model, is one of the most cutting-edge approaches that is widely applied to diverse vision and language tasks. It efficiently captures global information with linear complexity and compensates for the shortcomings of convolutional neural networks (CNNs) and conventional transformers. To this end, this article introduces a U-shaped deep learning model incorporating a large-window Mamba scale (LMS) module and a hierarchical feature fusion approach for echocardiographic segmentation. First, a cascaded residual block serves as an encoder and is employed to incrementally extract multiscale detailed features. It addresses the vanishing gradient issue by leveraging a residual structure that ensures stable and rapid convergence throughout the training process. Second, a large-window multiscale mamba module is integrated into the decoder to capture global dependencies across regions and enhance the segmentation capability for complex anatomical structures. Furthermore, our model introduces auxiliary losses at each decoder layer and employs a dual attention mechanism to fuse multilayer features both spatially and across channels. This approach enhances segmentation performance and accuracy in delineating complex anatomical structures. Finally, the experimental results using the EchoNet-Dynamic and CAMUS datasets demonstrate that the model outperforms other methods in terms of both accuracy and robustness. For the segmentation of the left ventricular endocardium (LVendo), the model achieved optimal values of 95.01 and 93.36, respectively, while for the left ventricular epicardium (LVₑₚᵢ), values of 87.35 and 87.80, respectively, were achieved. This represents an improvement ranging between 0.54 and 1.11 compared with the best-performing model.
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Yang et al. (2025) studied this question.
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