Why the study?
What baseline clinical and imaging variables predict progression to aortic valve replacement in asymptomatic patients with chronic aortic insufficiency?
Population
50 asymptomatic or minimally symptomatic patients with chronic aortic insufficiency and left ventricular…
Design
Cohort
Follow-up
median 44 months (range, 8 to 57)
Authors
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LV volume/function thresholds may flag higher progression risk in asymptomatic AI; leaves open whether they should guide surgical timing.
What baseline clinical and imaging variables predict progression to aortic valve replacement in asymptomatic patients with chronic aortic insufficiency?
Baseline measurements of left ventricular size and function, including end-systolic volume and exercise LVEF, can identify asymptomatic patients with chronic aortic insufficiency at higher risk for early progression to valve replacement.
Deirdre Siemienczuk (1989) studied this question.
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