Why the study?
The distribution of alleles and genotypes, and the association of T-786C eNOS3 and Lys198Asn EDN1 polymorphisms with hypertension in type 2 diabetes, required evaluation.
Are T-786C (eNOS3) and Lys198Asn (EDN1) gene polymorphisms associated with arterial hypertension in patients with type 2 diabetes mellitus?
Are T-786C (eNOS3) and Lys198Asn (EDN1) gene polymorphisms associated with arterial hypertension in patients with type 2 diabetes mellitus?
The CC genotype of the eNOS3 T-786C polymorphism is associated with the development of arterial hypertension and reduced endothelium-dependent vasodilation in patients with type 2 diabetes.
Polymorphisms in eNOS3 and EDN1 may associate with hypertension in type 2 diabetes; leaves open any role in risk stratification or therapy.
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Дубинина et al. (2019) studied this question.
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