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Abstract— trans ‐4‐aminocrotonic acid, dl ‐ cis ‐aminocyclohexane‐ltarboxylic acid and 4‐aminotetrolic acid were found to be competitive inhibitors of GABA uptake in rat brain slices. These inhibitors are analogues of extended conformations of GABA, which indicates that these conformations are important in the initial binding of this inhibitory transmitter to its transport carrier.
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Beart et al. (1972) studied this question.
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