SummaryIn a controlled rheumatoid arthritis series of 59 cases intra-articular nitrogen mustard and hydrocortisone compared with hydrocortisone alone gave a better effect in 32 per cent. The mean extension of the remission was 2.3 months. The best results were achieved in cases with minimal roentgenological changes (Stages I—II) where the disease was of short duration.
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Vainio et al. (1960) studied this question.