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August 20, 2026Proceedings of the National Academy of SciencesOpen Access

Morphogenesis of bacterial colonies in liquid crystalline environments

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Authors

SCSebastian Gonzalez La CorteTCThomas G. J. ChandlerSSSaverio E. Spagnolie

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Overview

Biophysical study reveals mechanical buckling and chain formation in bacterial colonies growing within liquid crystals, highlighting how anisotropic fluids shape microbial morphogenesis.

Key Points

  • To determine how anisotropic, viscoelastic liquid crystalline environments mechanically regulate the growth and colony morphology of proliferating bacteria.
  • Observed the proliferation and structural organization of multiple bacterial species cultured within nematic liquid crystal environments.
  • Developed a continuum mechanical framework to model the balance between growth-induced viscous stress and liquid crystal elasticity.
  • Bacterial cells across multiple species aligned along the nematic director to form single-cell-wide chains during reproduction.
  • As chains elongated, accumulated growth-induced viscous stresses overcame the elastic confinement of the nematic liquid crystal, resulting in localized buckling.

Cite This Study

Corte et al. (2026) studied this question.

synapsesocial.com/papers/6a86b4cb8a91293e6a1cc45ehttps://doi.org/10.1073/pnas.2536343123
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