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September 17, 2015Blood Coagulation & Fibrinolysis

Bioprostethic mitral valve thrombosis due to oral contraceptive drug use and management with ultra-slow thrombolytic therapy

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Population

1 female patient with obstructive bioprosthetic mitral valve thrombosis following oral contraceptive drug use

Design

Case_report

Authors

MYMahmut YesınMKMacit KalçıkSGSabahattin Gündüz

Discussion

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Overview

Should not yet change practice for bioprosthetic valve thrombosis; case report leaves open ultra-slow thrombolysis utility and contraceptive association.

Structured PICO

P
Population
1 female patient with obstructive bioprosthetic mitral valve thrombosis (BVT) following oral contraceptive drug use
I
Intervention
Ultra-slow thrombolytic therapy
O
Outcome
Successful management/resolution of obstructive BVT

This case highlights a novel potential association between oral contraceptive use and bioprosthetic valve thrombosis, which was successfully treated with ultra-slow thrombolytic therapy.

Cite This Study

Yesın et al. (2015) studied this question.

synapsesocial.com/papers/6a86b539f87adc0a02ca0639https://doi.org/10.1097/mbc.0000000000000420
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diagnosis and treatment of left-sided prosthetic valve thrombosis2007 · 35 citations
  2. 2Thrombolytic Therapy for the Treatment of Prosthetic Heart Valve Thrombosis in Pregnancy With Low-Dose, Slow Infusion of Tissue-Type Plasminogen Activator2013 · 184 citations
  3. 3Hormonal Contraceptives and Cerebral Venous Thrombosis Risk: A Systematic Review and Meta-Analysis2015 · 104 citations