Key result
Thrombolysis should be first-line therapy for left-sided prosthetic valve thrombosis if there are no contraindications and thrombus diameter is ≥5 mm, with an 80% success rate and 4% mortality.
Why the study?
What is the optimal diagnostic and treatment strategy for left-sided prosthetic valve thrombosis?
Population
Patients with left-sided prosthetic valve thrombosis (obstructive and nonobstructive forms)
Design
Review
Authors
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Thrombolysis may warrant first-line consideration for left-sided prosthetic valve thrombosis; leaves open need for larger RCTs to guide practice.
What is the optimal diagnostic and treatment strategy for left-sided prosthetic valve thrombosis?
Thrombolysis is recommended as the first-line therapy for left-sided prosthetic valve thrombosis with a thrombus diameter ≥5 mm, given its high success rate and acceptable safety profile compared to surgery.
M Lengyel (2007) conducted a review in Left-sided prosthetic valve thrombosis. Thrombolysis, surgery, and heparin was evaluated. Thrombolysis should be first-line therapy for left-sided prosthetic valve thrombosis if there are no contraindications and thrombus diameter is ≥5 mm, with an 80% success rate and 4% mortality.
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