Key result
Thrombolytic therapy, particularly with low-dose and slow-infusion rates of tissue plasminogen activator, has emerged as an effective and safe alternative to surgery for prosthetic valve thrombosis.
Why the study?
What are the current treatment options and their comparative efficacies for prosthetic heart valve thrombosis?
Population
Patients with prosthetic heart valve thrombosis (PVT)
Design
Review
Authors
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May support individualized decisions in prosthetic valve thrombosis; leaves open need for randomized trials before practice change.
What are the current treatment options and their comparative efficacies for prosthetic heart valve thrombosis?
This review highlights that low-dose, slow-infusion thrombolysis is emerging as an excellent alternative to traditional surgical therapy for prosthetic valve thrombosis.
Biteker et al. (2015) conducted a review in Prosthetic heart valve thrombosis. Thrombolytic therapy vs. Surgery was evaluated. Thrombolytic therapy, particularly with low-dose and slow-infusion rates of tissue plasminogen activator, has emerged as an effective and safe alternative to surgery for prosthetic valve thrombosis.
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