What question did this study set out to answer?

To develop a preoperative predictive model and web-based application (OviR0) to estimate the feasibility of complete cytoreduction following neoadjuvant chemotherapy in advanced serous ovarian cancer.

August 20, 2026Asian Journal of OncologyOpen Access

OviR0: A novel application for assessing the feasibility of complete cytoreduction and hyperthermic intraperitoneal chemotherapy in epithelial ovarian cancer following neoadjuvant chemotherapy

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To develop a preoperative predictive model and web-based application (OviR0) to estimate the feasibility of complete cytoreduction following neoadjuvant chemotherapy in advanced serous ovarian cancer.
Retrospective single-center study analyzing 61 female patients (mean age 55 years; 65.6% FIGO Stage III) with serous ovarian neoplasms treated between January 2022 and January 2024 with neoadjuvant chemotherapy followed by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
Demographic factors, comorbidities, post-chemotherapy CA-125 levels, and Peritoneal Carcinomatosis Index (PCI) were evaluated using multivariable logistic regression to construct a nomogram and a web-based decision tool.
Univariate analysis identified patient age, number of comorbidities, post-chemotherapy CA-125 levels, and PCI score as significant predictors of achieving CC-0/CC-1 complete cytoreduction.
The multivariable predictive model demonstrated an overall accuracy with an area under the receiver operating characteristic curve (AUC) of 97.17% (0.9717).

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Implication

Retrospective study demonstrates high predictive accuracy for complete cytoreduction and HIPEC in ovarian cancer following chemotherapy, highlighting improved surgical planning.

Cite This Study

Shouptik Basu (2026) studied this question.

synapsesocial.com/papers/6a86b57f8a91293e6a1ccdb5 https://doi.org/10.25259/asjo_97_2025

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Implication

Retrospective study demonstrates high predictive accuracy for complete cytoreduction and HIPEC in ovarian cancer following chemotherapy, highlighting improved surgical planning.

OviR0: A novel application for assessing the feasibility of complete cytoreduction and hyperthermic intraperitoneal chemotherapy in epithelial ovarian cancer following neoadjuvant chemotherapy

Key Points

Discussion

Implication

Cite This Study

OviR0: A novel application for assessing the feasibility of complete cytoreduction and hyperthermic intraperitoneal chemotherapy in epithelial ovarian cancer following neoadjuvant chemotherapy

Key Points

Discussion

Implication

Cite This Study

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