The Lifelong Imprint of Air Pollution in Cystic Fibrosis: Where We Are and Next Steps

Meghan E. McGarry; Rhonda D. Szczesniak

doi:10.1093/annalsats/aaoag244

August 18, 2026Annals of the American Thoracic Society

The Lifelong Imprint of Air Pollution in Cystic Fibrosis: Where We Are and Next Steps

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Key Points

To review the lifelong health consequences of ambient air pollution exposure in individuals with cystic fibrosis and outline critical future directions for research and clinical management.
Synthesized current clinical and epidemiological literature examining ambient air pollution exposure and health outcomes across the lifespan in cystic fibrosis.
Evaluated methodological challenges and evidence gaps concerning acute and cumulative pollutant exposures.
Ambient air pollution exposure correlates with accelerated lung function decline, increased pulmonary exacerbations, and worsened long-term respiratory outcomes.
Highlights urgent priorities for fine-scale longitudinal exposure assessment, mechanistic research, and proactive environmental health interventions in cystic fibrosis care.

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Implication

Narrative review explores the lifelong consequences of air pollution in cystic fibrosis, highlighting key targets for future environmental health research.

Abstract

Meghan E McGarry, Rhonda D Szczesniak; The Lifelong Imprint of Air Pollution in Cystic Fibrosis: Where We Are and Next Steps, Annals of the American Thorac

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McGarry et al. (2026) studied this question.

synapsesocial.com/papers/6a86b5eb8a91293e6a1cd813 https://doi.org/10.1093/annalsats/aaoag244

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The Lifelong Imprint of Air Pollution in Cystic Fibrosis: Where We Are and Next Steps

Key Points

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Abstract

Discussion

Cite This Study

The Lifelong Imprint of Air Pollution in Cystic Fibrosis: Where We Are and Next Steps

Key Points

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Implication

Abstract

Discussion

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