CONVINCE in the context of existing evidence on haemodiafiltration

Robin W.M. Vernooij; Michiel L. Bots; Giovanni FM Strippoli; Bernard Canaud; Krister Cromm; Mark Woodward; Peter J. Blankestijn; Andrew Davenport; Bernard Canaud; Cláudia Barth; Giovanni FM Strippoli; Jörgen Hegbrant; Kathrin I. Fischer; Krister Cromm; Mariëtta Török; Mark Woodward; Matthias Rose; Michiel L. Bots

doi:10.1093/ndt/gfac019

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Abstract

Haemodiafiltration (HDF) provides a greater removal of larger solutes and protein-bound compounds than conventional high-flux haemodialysis (HD). There are indications that the patients receiving the highest convection volumes of HDF result in improved survival compared with HD. However, the comparative efficacy of HDF versus HD remains unproven. Here we provide a comparative account of the methodology and aims of 'the comparison of high-dose HDF with high-flux HD' (CONVINCE) study in the context of the totality of evidence and how this study will contribute to reaching a higher level of certainty regarding the comparative efficacy of HDF versus HD in people with end-stage kidney disease.

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Vernooij et al. (2022) studied this question.

synapsesocial.com/papers/6a86b8daa810ea404bcf7e96 https://doi.org/10.1093/ndt/gfac019

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CONVINCE in the context of existing evidence on haemodiafiltration

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CONVINCE in the context of existing evidence on haemodiafiltration

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