Why the study?
Is coronary flow reserve decreased in haemodialysis patients compared to non-renal failure patients without significant LAD stenosis?
Population
41 patients who had undergone coronary angiography, consisting of 21 haemodialysis patients with no…
Comparison
Haemodialysis (end-stage renal disease) vs Non-renal failure patients without LAD stenosis
Design
Cross-sectional
Authors
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Reduced CFR in haemodialysis patients may signal microvascular dysfunction; hypothesis-generating and requires prospective outcome studies before clinical adoption.
Is coronary flow reserve decreased in haemodialysis patients compared to non-renal failure patients without significant LAD stenosis?
Haemodialysis patients exhibit decreased coronary flow reserve due to elevated baseline peak coronary velocities, which may be related to cardiac hypertrophy and anaemia.
Niizuma et al. (2008) studied this question.
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