After injection of glucagon, growth hormone increased to 8.0 ng per milliliter or more in 33 of 34 subjects without apparent pituitary disease. In 21 of 23 patients with pituitary disease the maximum value did not exceed 4.8 ng per milliliter. The glucagon stimulation test is a safe, convenient and reasonably reliable way of testing for growth-hormone deficiency.
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Mitchell et al. (1970) studied this question.
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