Isolated Thyrotropin Deficiency

Article1 June 1964Isolated Thyrotropin DeficiencyReview and Report of Three CasesFRANCIS N. LOHRENZ, M.D., RAFAEL FERNANDEZ, M.D., RICHARD P. DOE, M.D.FRANCIS N. LOHRENZ, M.D.Search for more papers by this author, RAFAEL FERNANDEZ, M.D.Search for more papers by this author, RICHARD P. DOE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-6-990 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCase reports of patients with isolated deficiency of one of the tropic hormones of the pituitary gland are now well-documented, although panhypopituitarism is still by far the more common disorder (1-4). Of these isolated deficiencies, inadequate gonadotropin secretion is the most common. Tumors, idiopathic atrophy, or infarctions of the pituitary gland in adults may present with the features of hypogonadotropic hypogonadism and develop thyrotropin-stimulating hormone (TSH) and adrenocorticotropic hormone (ACTH) deficiency later in their course (1, 5, 6). Prepubertal hypogonadtropic hypogonadism also may be due to a space occupying lesion, infarction, idiopathic atrophy, or be a phase of severe debilitating...References1. PETERSGERMANMANWELT JPWJEBLG: Function of gonads, thyroid, and adrenals in hypopituitarism. Metabolism 3: 118, 1954. MedlineGoogle Scholar2. MADDOCKLEACHKLEINMYERS WORBSPGB: Selective pituitary failure: an example characterized by deficient ACTH and gonadotrophin secretion with intact thyrotrophin secretion. Amer. J. Med. Sci. 226: 509, 1953. CrossrefMedlineGoogle Scholar3. GANONGHUME WFDM: Effect of graded hypophysectomy on thyroid, gonadal, and adrenocortical function in the dog. Endocrinology 59: 293, 1956. CrossrefMedlineGoogle Scholar4. 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Doe, M.D., Chief, Metabolic Section, Veterans Administration Hospital, 54th Street and 48th Avenue South, Minneapolis, Minnesota 55417. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA Case of Isolated Thyroid Stimilating Hormone DeficiencyA Case of Idiopathic Thyrotropin TSH DeficiencyIsolated TSH deficiency with a partially empty sellaCentral Hypothyroidism—Trophoprivic HypothyroidismFamilial Isolated Thyrotropin Deficiency with CretinismAcral Changes in Thyroid DisordersDie pathologische Morphologie der endokrinen RegulationsstörungenEndokrinologie in der KinderheilkundeInhibitors of adrenal cortical functionPseudohypoparathyroidism and selective deficiency of thyrotropin: An interesting associationHypopituitarism: A Study of Growth Hormone and Other Endocrine FunctionsMITCHELL T. RABKIN, M.D., ANDREW G. FRANTZ, M.D.Inhibitors of adrenal cortical function 1 June 1964Volume 60, Issue 6 Page: 990-998 Keywords Adrenocorticotropic hormone Atrophy Hospital medicine Hypogonadism Infarction Medical services Pituitary gland Prolactin Thyroid Thyroid-stimulating hormone ePublished: 1 December 2008 Issue Published: 1 June 1964 PDF downloadLoading ...